Anyone familiar with Loleris's ProfileService?

Datastores are a foreign concept to me I have never really gotten around to getting the hang of it. I know Profileservice is incompatible with global leaderboards, so I was going to save a custom key outside of profileservice, while using profile service for players. I don’t quite understand the limitations on data sending though, I would exercise restraint and only update the “global leaderboard” every couple minutes. Would this interfere with Profileservice? I saw nothing of this sort reading through the api.