As a Roblox developer, it is currently too hard to use high DPI displays with Roblox Studio (and the client). There have been many, many, many, many threads about high DPI over the years, all marked as bug reports.
However, it seems that high DPI support is a missing feature, not a bug. Proper high DPI support was supposedly only recently made possible with the upgrade of the Qt framework, that has been previously mentioned by staff members in many of the above threads.
If Roblox is able to address this issue, it would improve my development experience because I would not need to choose between manually overriding scaling settings (and getting tiny UI in some places as a consequence) and having blurry, unreadable UI.