The keys listed above are used for mouse-free navigation of instances within your explorer in studio, however while playtesting this behaviour still happens even if your mouse is within the viewport. I’m using the [End] key on my keyboard as an important time-saving debugging hotkey for my framework (to set the game timer to 0 to skip ahead) but the Explorer navigation sinks my input and the hotkey does not trigger (using the new IAS).
I consider this a bug because when in test mode the behaviour is inconsistent. If I press [Home] or [End] it will select an object in the Explorer, but if I then unselect the object and click back into the viewport, these keys will no longer be sunk by studio and I can now use my custom IAS debug hotkeys.