Okay. Then something like this should work:
-- Server code
local part = <your part>
local prevCFrame = part.CFrame
local detectChange = game:GetService("RunService").HeartBeat:Connect(function()
if part.CFrame ~= prevCFrame then
part:Destroy()
detectChange:Disconnect() -- I have not used this before, but I think this is correct.
end
end)