Yes it’s far more better than Vector3, allows more freedom and access to far more options.
One of the major impacts of CFrame is that that axis is local and based on where your part is not the world space/direction of that part, that’s what I meant by saying in their own matrix
Also that CFrame contains the Coordinate Frame as well as the LookVector.
I’ll link AxisAngle’s great resource and explanation on it: How to think about CFrames
But as a general answer to your question, yes CFrames are better.