Do you have a script for it yet?
If so, please show it.
Edit: what I would do is create boolvalue inside of the part then call the boolvalue “Touched” then whenever the player touches the part it checks if the boolvalue is true, if it is not true then it will play the sound then make the boolvalue true
Example code:
local Sound = (sound)
(code when the player touches the part):Connect(function()
if script.Parent.Touched.Value = false then
Sound:Play()
else
end