This bug happens to me sometimes, but not odten. Select a part in the explorer tab, press F to go to it, and then you should have the ability to rotate your camera, select parts, if not then you have a unique problem.
It is something to do with collision groups. For me it was that default was set to not collide with itself that broke it.
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I found a better solution you just have to find that invisible frame (for me it was a invisible frame) and then just toggle the “Interactable” property.
It will tell studio that you’re not interacting with the invisible frame but with the game itself.
Edit: Apparently it disables everything inside of it too… Maybe it wasn’t a better solution. 
yea, ever since roblox created that property, UIs have been 10x more annoying to manage.
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I highly agree with you, House_Owner. 
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I found a ACTUAL fix and it is to just toggle the “Active” property on the element that is blocking your mouse.
This HAS to work.
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I had this situation happen to me when I made my Viewmodel into a WorldModel, instead of just a Model. I don’t know if it is related exactly, but I couldn’t select it without dragging or explorer, and it refused to be moved while in studio.
Im having the same issue and it’s affecting both in studio were i cant drag parts or click em’ but mine doesn’t even work in game like ClickDetec or anything related to clicking is just simply not working…
restarted Pc, Updated studio, nothing works.
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