I was dragging around a model of a physics-based car (so each wheel has attachments, cylindrical constraint and a spring constraint) when I suddenly got a giant error in the output window. After the error occurred, multiple problems starting happening. I clicked a different part to resize it and the previous arrows didn’t delete themselves as seen below. The L indicating local movement was stuck to the middle of the screen. Ultimately I had to restart studio as it was very hard to use after this point.
There’s a known issue where you try to resize a selection containing multiple objects, where none of those objects are parts/models (you only have Attachments / Constraints selected), it will break. Since you say you were working with constraints that’s likely what happened.