There should be an explanation on what Region3 is on its API reference page

https://developer.roblox.com/api-reference/datatype/Region3

All that is documented is the properties and functions, but now what Region3’s themselves are.

A Region3 is a section of the world, a representation of location and size of a 3D area from one corner to its opposite corner.

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This picture helped me alot.
(I only have found this one which is edited)
08af7cada4ebfd3bd653636784765bf8b303fd26

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